How much does a box of Palbociclib cost?

Palbociclib (Palbociclib) is indicated for the treatment of men or premenopausal/perimenopausal/postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer. It can be used in combination with an aromatase inhibitor as initial endocrine therapy, and in combination with fulvestrant for the treatment of men or women with disease progression after endocrine therapy.

Palbociclib is an oral capsule that is usually taken once a day with food during the first 21 days of a 28-day cycle. The doctor will decide how many times the patient should repeat this cycle based on the severity of the condition, drug response, etc. It is recommended to take palbociclib at about the same time every day, and not to take more or less than the number prescribed by the doctor. If a patient vomits after taking palbociclib, do not take additional doses and continue with the regular dosing schedule. If you experience certain side effects, your doctor may reduce your dose or stop treatment temporarily or permanently.

The original drug of palbociclib has been launched in China and has entered the scope of Class B medical insurance, but reimbursement is limited to patients who meet the indications. The price of each box may be more than more than 4,000 yuan. The price of palbociclib's original drug, 125mg*21 capsules, per box sold overseas may be more than RMB 10,000 (the price may fluctuate due to exchange rates). There are also generic palbociclib drugs produced in other countries. The price of 125mg*21 tablets produced by Bangladesh pharmaceutical factory may be around 900 yuan per box (the price may fluctuate due to the exchange rate), which is cheaper. The pharmaceutical ingredients of generic drugs are basically the same as those of domestic and foreign original drugs.