How effective is ldelalisib?

Idelalisi, as a PI3Kδ inhibitor, mainly targets B cells, which is beneficial for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are critical because both diseases involve abnormally increased numbers of B lymphocytes. Here is some important information about the efficacy of idelalix in these two diseases:

1.Therapeutic response rate: Idelalistat has been shown to produce significant therapeutic responses in some patients in clinical trials. Specifically, it can lead to a reduction in lymph node size, a reduction in white blood cell counts, and relief of other disease-related symptoms.

2.Prolonged survival: Idelalistat has been shown in some studies to prolong the survival of patients, especially those who have received other treatments without adequate efficacy. However, the exact degree of survival improvement will vary for each patient.

3.Symptom relief: Many CLL and SLL patients experience symptoms such as swollen lymph nodes, fatigue, and night sweats. Idelalistat can help reduce these symptoms and improve patients' quality of life.

4.Quality of life: The disease itself and treatment may have a negative impact on the patient's quality of life. By reducing symptoms and providing therapeutic response, idelalix has the potential to improve patients' quality of life, allowing them to better cope with the challenges of leukemia and lymphoma.

It should be noted that the effectiveness of idelalix will vary from patient to patient and depends on many factors, including the severity of the disease, the patient's overall health, and whether they have received other treatments. In addition, because idelalix is u200bu200ba targeted drug, it generally has lower systemic toxicity than traditional chemotherapy drugs, which can help reduce discomfort during treatment.

Idelalis is not currently available in the country, so it is not included in medical insurance. Patients cannot purchase it domestically and need to purchase it through overseas channels. There are only original drugs of iderallis available abroad, mainly from the United States, and the price is as high as about 38,000 yuan.