Is ozanimod an immunosuppressive drug?

Ozamod (ozanimod) is an immunosuppressive drug. It belongs to a class of drugs called selective immunomodulators (S1P receptor modulators). Ozamod inhibits the immune response by inhibiting the migration of specific immune cells and reducing the activity of the immune system. It is commonly used to treat autoimmune diseases such as multiple sclerosis and ulcerative colitis.

Ozamod affects the immune system by blocking the migration of lymphocytes from lymph nodes into the blood, intestines, central nervous system, and inflammatory tissues. Because Ozamod modulates lymphocyte function, it may increase the risk of infection. Ozamod reduces the number of circulating lymphocytes to approximately 45% of baseline values. Although rare, life-threatening and fatal infections have occurred in patients receiving ozanimod. Coadministration of ozanimod with antineoplastic drugs, noncorticosteroid immunosuppressive drugs, or immunomodulatory drugs may also increase the risk of immunosuppression and these treatments may be contraindicated. Live-attenuated vaccines should also be avoided during treatment with ozanimod and for 3 months after treatment. Before initiating treatment with ozanimod, it is recommended that antibody-negative patients undergo a full course of varicella vaccination, which should be done at least 4 weeks before initiating treatment with ozanimod.

The original drug Ozamod has been launched in China, but it has been on the market for a short time and has not been included in the medical insurance. The specific price is not yet clear, and domestic purchase channels are relatively difficult. The price of Ozamod original drug specifications0.92*28 capsules per box listed overseas may be around 19,000 yuan (the price may fluctuate due to the exchange rate), which is expensive. There is currently no generic version of Ozamod produced and launched. For more drug information and specific prices, please consult the medical consultant of Yaode.