Efficacy and effects of Lenalidomide

Lenalidomide (Lenalidomide) is an immunomodulatory drug with a wide range of clinical applications. It is mainly used to treat multiple myeloma (Multiple Myeloma), high-risk myelodysplastic syndrome (MDS) and other diseases. Its efficacy and mechanism of action are very complex, but overall, it affects the immune system and tumor cells in multiple ways to achieve therapeutic purposes. The following is a detailed introduction to the main functions and effects of lenalidomide:

1. Inhibiting the proliferation of tumor cells: One of the important functions of lenalidomide is to inhibit the proliferation of tumor cells. Multiple myeloma is a disease caused by the abnormal proliferation of malignant plasma cells in the bone marrow. Lenalidomide controls the progression of the disease by interfering with the growth and division of tumor cells, reducing the number of cancer cells.

2. Regulate the immune system: Lenalidomide can enhance the body's immune response. It activates and enhances the activity of T cells, which play a key role in the immune system and help identify and eliminate abnormal tumor cells. By boosting the activity of the immune system, lenalidomide helps the body better fight multiple myeloma and other cancers.

3. Reduce angiogenesis: Lenalidomide can also limit the blood supply to tumors by reducing angiogenesis around tumor cells. This makes it difficult for tumor cells to get enough oxygen and nutrients, inhibiting their growth and spread.

4. Improve hematopoietic function: For patients with high-risk myelodysplastic syndrome (MDS), lenalidomide can improve the production of blood cells in the bone marrow and reduce symptoms such as anemia. It helps restore normal hematopoietic function and increases hemoglobin levels in the blood.

5. Reduced disease symptoms: After treatment with lenalidomide, many patients report a reduction in symptoms associated with multiple myeloma or MDS such as fatigue, bone pain, anemia and risk of infection. These improvements help improve patients' quality of life.

6. Maintenance of remission: For patients with multiple myeloma, lenalidomide is often used as maintenance therapy after initial treatment. This helps extend the patient's remission period and reduces the risk of disease recurrence.

In short, the efficacy and effects of lenalidomide are multi-faceted. It provides an effective option for the treatment of multiple myeloma, high-risk myelodysplastic syndrome and other diseases by inhibiting the proliferation of tumor cells, regulating the immune system, reducing angiogenesis, improving hematopoietic function and alleviating disease symptoms. However, patients must use this medication correctly under the supervision of a doctor, as it may trigger some side effects that require regular monitoring and management.

Lenalidomide has been launched in China and has been included in medical insurance. Patients can purchase it domestically. The price is around 3,500~4,000 yuan. Due to different medical insurance policies in various places, the price also varies. Please consult your local pharmacy for specific prices. There are also original research drugs in China, but the price is as high as tens of thousands of yuan, so it is not recommended to buy them. The cheaper ones abroad are mainly generic drugs, including those from India, Bangladesh, and Laos, which cost about a few hundred yuan per box. The ingredients of foreign generic drugs and domestic lenalidomide drugs are basically the same.