How to take Ofatumumab

Ofatumumab can be used alone or in combination. The recommended dose for the treatment of Multiple Sclerosis (MS) is: 20 mg by subcutaneous injection initially at weeks 0, 1, and 2, followed by 20 mg subcutaneously once a month starting at week 4. The recommended doses and regimens of ofatumumab and chlorambucil in the treatment of chronic lymphocytic leukemia (CLL) are as follows: 300mg on 1 day, 1000mg on day 8 1 week later (cycle 1), 1000mg on day 1 of subsequent 28-day cycles, for a minimum of 3 cycles until optimal response or a maximum of 12 cycles.

The recommended dose and regimen of ofatumumab in combination with fludarabine and cyclophosphamide is: 300 mg on day 1, 1 week later 1000 mg on day 8 (cycle 1), and 1000 mg on day 1 of subsequent 28-day cycles for up to 6 cycles. The recommended dose and regimen of extended treatment with ofatumumab monotherapy is: 300 mg on day 1, 1000 mg on day 8 after 1 week, 1000 mg after 7 weeks, and every 8 weeks thereafter for up to 2 years. The recommended dose and regimen of ofatumumab for the treatment of refractoryCLL is 12 doses. The administration method includes: 300 mg initial dose on day 1 for 1 week, followed by 2000 mg weekly for 7 doses (2nd to 8th infusion) for 4 weeks, and then 2000 mg every 4 weeks. mg for 4 doses (9th to 12th infusion).

The recommended dose of ofatumumab is ofatumumab. The original drug of ofatumumab has been launched in China and has also been included in medical insurance. Reimbursement is only available to patients who meet the indications. The price is around tens of thousands of yuan, and domestic purchase channels are relatively difficult. The European version of ofatumumab original drug specifications20mg/0.4mL each sold overseas may cost around RMB 16,000 (the price may fluctuate due to the exchange rate). It is expensive and there are currently no generics of ofatumumab. For more drug information and specific prices, please consult a medical consultant.