What are the side effects of Olaparib?

Olaparib is an oral drug approved to treat advanced ovarian, fallopian tube and peritoneal cancers, including breast cancer, pancreatic cancer, and metastatic prostate cancer (which have spread in the body). It is also approved as adjuvant treatment for HER2-negative, BRCA-mutated, high-risk early-stage breast cancer.

In olaparib clinical studies,the most common adverse reactions reported in ≥10% of patients were nausea, fatigue, anemia, vomiting, diarrhea, decreased appetite, headache, dysgeusia, cough, neutropenia, dyspnea, dizziness, dyspepsia, leukopenia, and thrombocytopenia. After olaparib was put on the market, adverse events such as allergies (including angioedema), erythema nodosum, rash, and dermatitis occurred. In clinical studies of the combination treatment of olaparib and bevacizumab, common adverse reactions in ≥10% of patients were nausea, fatigue (including asthenia), anemia, lymphopenia, vomiting, diarrhea, neutropenia, leukopenia, urinary tract infection, and headache.

Lynparza The original drug has been launched in China and has entered the scope of Class B medical insurance, but it is only available to patients who meet the indications. The price of each box of 150mg*56 tablets may be around RMB 6,000. There are price differences for drugs of different specifications. There are also Olaparibgeneric drugs produced overseas. The specifications produced by Bangladesh pharmaceutical factories150mg*120 tablets per box may cost around RMB 4,000 (the price may fluctuate due to the exchange rate). Its drug ingredients are basically the same as those of the Olaparib original drug. For more drug information and specific prices, please consult Yaode Medical Consultant.