How much does a course of Obinutuzumab cost?

Obinutuzumab is a humanized anti-CD20 monoclonal antibody developed by GlycArt Biotechnology Developed by AG and developed by Roche for cancer treatment, it can be used as a first-line treatment in chronic lymphocytic leukemia in combination with chemotherapy or in combination with venetoclax, as a first-line treatment in follicular lymphoma in combination with chemotherapy, and as a treatment in relapsed or refractory follicular lymphoma in combination with bendamustine.

In contrast to the classictype I CD20 antibodyrituximab, otuzumabbindstype II CD20 antibody. This results in otuzumab having higher antibody-dependent cytotoxicity induction and higher direct cytotoxic effects than classicalCD20 antibodies. The recommended dose for chronic lymphocytic leukemia is 100 mg on day 1 of cycle 1, 900 mg on day 2, 1000 mg on days 8 and 15 of cycle 1, and 1000 mg on day 1 of cycles 2-6. The recommended dose for follicular lymphoma is 1000 mg on days 1, 8, and 15 of cycle 1, 1000 mg on day 1 of cycles 2-6 or cycles 2-8, then 1000 mg every 2 months for up to 2 years.

The original drug of Otuzumab has been launched in China and has entered the scope of medical insurance, but it is only reimbursed for patients who meet the indications. Specifications The price of 1000mg (40ml)*1 bottle may be around 9,000 yuan. It is estimated that the price of a course of treatment may be tens of thousands to hundreds of thousands of yuan, which is expensive. The price of the Turkish version of Otuzumab Specifications1000mg/40ml per box listed overseas may be around RMB 10,000 (the price may fluctuate due to the exchange rate). The ingredients of the original drugs sold domestically and abroad are basically the same. There is currently no generic version of Otuzumab produced and launched. For more drug information and specific prices, please consult the medical consultant of Yaode.