Are Zepzelca and Lurbinectedin the same medicine?

Lurbinectedin (Zepzelca) and rubicatin (Lurbinectedin) are actually the same drug, they just have different names. The drug's international nonproprietary name (INN) is Lurbinectedin, and the drug is often given different brand names in different markets and countries. Thus, lubicidine and rubicatin are both commercial names for lurbinectedin, which is used to treat certain types of cancer.

Lurbinectedin (or rubicatin, rubicatin) is a DNAtopoisomerase Ⅱα inhibitor. It interferes with the DNA repair and replication of cancer cells by affecting the topological structure of DNA, ultimately leading to cancer cell death. The drug has been approved to treat recurrent small cell lung cancer (SCLC) and recurrent synovial sarcoma (Myxoid/round cell liposarcoma), providing a new treatment option for patients with these cancer types.

Different trade names may be used in different countries and regions, depending on the drug's registration and marketing strategy. Therefore, when it comes to Lurbinectedin, patients and physicians need to pay attention to the drug's International Nonproprietary Name (INN) as well as its trade name in specific markets to ensure proper identification and use of this drug.

In short, Lurbinectedin (Zepzelca) and Rubicatin (Lurbinectedin) represent the same drug with the same therapeutic effect and mechanism of action, but they use different names in different markets. It is a promising treatment that offers new hope for patients with certain types of cancer. Treatment decisions should be made jointly by physician and patient, taking into account the patient's specific condition and treatment goals.

Rubicatin has not yet been launched in China, so it is not included in medical insurance. Patients cannot purchase it domestically and need to purchase Rubicatin through overseas channels. There is only the original drug Rubicatin in foreign countries, and the price is relatively expensive. In comparison, the original drug in Singapore is slightly cheaper, priced at more than 30,000, and there are other American versions of the original drug, priced at more than 90,000.