What medicines cannot be taken with molnupiravir capsules?

Molnupiravir capsules (Molnupiravir) is a drug used to treat COVID-19. It may interact with other drugs, so patients need to be cautious when using monogravir capsules and should inform their doctors about all the drugs they are taking. The following are some drugs or drug classes that should not be used with monogravir capsules, as well as possible interactions:

1. Anti-acid drugs (proton pump inhibitors and H2 receptor antagonists): Proton pump inhibitors (such as omeprazole, lansoprazole) and H2 receptor antagonists (such as ranitidine, famotidine) are used to treat acid reflux and ulcer disease. Monolavir capsules may affect the absorption of these drugs, so dose adjustments or other measures may be necessary when used together. Patients should use these medications under a doctor's supervision.

2. Anticoagulant drugs: Anticoagulant drugs (such as warfarin, aspirin) are used to prevent thrombosis. Monolavir capsules may affect the metabolism of these drugs, so coagulation parameters need to be monitored closely and anticoagulant doses adjusted if needed.

3. Immunosuppressive drugs: Immunosuppressive drugs are usually used after organ transplantation or for the treatment of autoimmune diseases. Monolavir capsules may affect the function of the immune system, so use of these medications requires special caution and monitoring as recommended by your doctor.

4. Anti-epileptic drugs: Anti-epileptic drugs (such as carbamazepine, fenobarbisate) are used to treat epilepsy. Monolavir capsules may affect the concentrations of these drugs, so close monitoring is required during concurrent use and antiepileptic drug dosage adjustments may be necessary.

5. Diuretics: Diuretics (eg, furosemide, torsemide) are used to control fluid balance and high blood pressure. Monoravir capsules may affect the excretion of these drugs, so fluid balance needs to be monitored with special care to avoid discomfort.

6. Ketoconazole (Ketoconazole): Ketoconazole is an antifungal drug that may interact with monogravir capsules, so you need to be careful when using it, and you may need to adjust the dose or take other measures.

It is important to emphasize that the interactions listed above are not absolute and may vary depending on individual differences and specific circumstances. Before using monogravir capsules, patients should inform their doctor about all medications they are taking, including prescription drugs, over-the-counter drugs, supplements, and herbal medicines. Doctors will take the patient's medication history into consideration and determine whether treatment adjustments need to be made to ensure safe and effective treatment. Patients should not stop or change the dosage of any medication on their own but should do so under the guidance of a physician.

Monolavir capsules are already on the market in China, but are not yet included in medical insurance. Please consult your local hospital pharmacy for specific prices. The cheaper ones abroad are Indian generic drugs, which cost around three to four hundred yuan, and the ingredients of domestic original drugs and foreign generic drugs are basically the same.