Is Neratinib a targeted drug?

Neratinib (Neratinib) is a targeted therapy that acts on a protein called human epidermal growth factor receptor2 (HER2). The HER2 protein allows cells to divide and grow. Some cancers have large amounts of the HER2 protein, which can cause cancer cells to divide and grow faster. Neratinib works by locking HER2 on cancer cells, so it stops the cells from growing.

Unlike chemotherapy, which tends to kill all rapidly dividing cells, neratinib targets only those cells with specific receptors that are found in abnormally high numbers inHer2-positive breast cancer cells. Neratinib binds to these receptors, inhibiting their activity, their ability to direct the activity of other cells, and tumor growth. Although neratinib is a targeted therapy, it is different from other targeted therapies such as trastuzumab or pertuzumab, which are immune-targeted therapies. Immune-targeted therapies are like antibodies produced by our immune system. Neratinib is not an antibody.

NeratinibThe original drug is marketed in China as neratinib maleate tablets and is covered by Class B medical insurance, but reimbursement is limited to patients who meet the indications. SpecificationsThe price of each box of 40mg*180 tablets may be around 7,000 yuan. Generic drugs of neratinib are also sold overseas. The drug ingredients are basically the same as those of the original drug. The price of 40mg*180 tablets produced by Bangladesh pharmaceutical factory may be around 4,000 yuan per box (the price may fluctuate due to the exchange rate). For more information about overseas drugs and specific prices, please consult Yaode Medical Consultant.