Contraindications while taking neratinib

Neratinib (Neratinib) is a drug that prevents the growth of cancer cells to treat breast cancer. This type of cancer occurs when cells in the breast grow and divide in an uncontrolled way. Patients can take this drug orally with a glass of water as directed. Do not drink grapefruit juice while taking this drug. Grapefruit may inhibit CYP3A metabolism and may increase the serum concentration of neratinib.

Try to avoid using neratinib together with other drugs to avoid drug interactions, such as avoiding the simultaneous use of proton pump inhibitors (PPI) and neratinib; taking neratinib at least 2 hours before the next dose of H2 receptor antagonist or 10 hours after the H2 receptor antagonist; administering neratinib alone 3 hours after antacids. It is recommended that women of childbearing potential use effective contraception while taking neratinib and for ≥1 month after stopping the drug. It is recommended that the partners of such women use effective contraception while taking neratinib and for 3 months after the last dose.

NeratinibThe original drug is marketed in China as neratinib maleate tablets and is covered by Class B medical insurance, but reimbursement is limited to patients who meet the indications. SpecificationsThe price of each box of 40mg*180 tablets may be around 7,000 yuan. Generic drugs of neratinib are also sold overseas. The drug ingredients are basically the same as those of the original drug. The price of 40mg*180 tablets produced by Bangladesh pharmaceutical factory may be around 4,000 yuan per box (the price may fluctuate due to the exchange rate). For more information about overseas drugs and specific prices, please consult Yaode Medical Consultant.