Why is Melphalan/Melphalan used for transplantation?

Melphalan/Melphalan (Melphalan) is used during stem cell transplantation to achieve specific therapeutic goals, especially for the treatment of some malignant blood diseases, such as multiple myeloma (Multiple Myeloma) and lymphoma (Lymphoma). Here are the reasons why melphalan/melphalan is used during transplantation:

1.Preparing the bone marrow space: A stem cell transplant typically involves injecting healthy stem cells (usually autologous stem cells, stem cells from the patient's own body, or allogeneic stem cells, stem cells from a donor) into the patient to rebuild or repair the patient's blood system. Before a stem cell transplant, the patient's bone marrow space usually needs to be prepared so that new stem cells can successfully colonize and differentiate. Melphalan/Melphalan High-dose pretreatment can help remove abnormal blood cells and interfering cells in patients, thereby providing more space for new stem cells to grow and colonize.

2.Removal of cancer cells: Melphalan/MelphalanPretreatment helps eliminate leukemia or lymphoma cells in patients during stem cell transplantation. This is particularly important because before performing a stem cell transplant, the presence of malignant cells needs to be reduced or eliminated as much as possible to increase the success rate of the transplant and the effectiveness of the treatment.

3.Immunosuppression: Melphalan/Melphalan also has an immunosuppressive effect, helping to reduce the patient's immune response. This is important during a stem cell transplant because the immune system may attack the newly injected stem cells, causing the transplant to fail. By suppressing the immune response, Melphalan may reduce the risk of rejection of transplanted stem cells.

Melphalan/MelphalanOral medicines and injections have been launched in China. Oral medicines have been included in medical insurance, but injections have not yet been included in medical insurance. For specific prices and reimbursement, please consult the local hospital pharmacy and the local medical insurance bureau. Foreign original drugs include European original drugs and Turkish original drugs. European original drugs cost about more than a thousand yuan, and Turkish original drugs cost about a few hundred yuan. In addition, there are Indian generic drugs, the price of which is also around a few hundred yuan. The ingredients of original drugs and generic drugs are basically the same.