Where to buy Necitumumab
Necitumumab is a monoclonal antibody that blocks a protein in the body that affects the growth of tumor cells. Monoclonal antibodies can only target and destroy certain cells in the body. This may help protect healthy cells from damage. Nexituzumab is used to treat certain types of non-small cell lung cancer, often in combination with other cancer drugs, such as gemcitabine and cisplatin.
Nexituzumab is also an EGFR antagonist that works by binding to the epidermal growth factor receptor (EGFR) and preventing the binding of its ligands, a process involved in cell proliferation, metastasis, angiogenesis, and malignant progression. Nexituzumabbinding to EGFR induces receptor internalization and degradation. Strict monitoring for adverse events such as cardiopulmonary arrest, hypomagnesemia, venous and arterial thromboembolic events, cutaneous toxicity, and infusion-related reactions is recommended during use of nesituzumab. Because of the increased toxicity and mortality observed in the treatment of non-squamous NSCLC, nexituzumab is only recommended for the treatment of squamous NSCLC in combination with cisplatin and gemcitabine. Animal studies indicate potential embryo-fetotoxicity.
The patent drug Nexituzumab has not yet been approved for marketing in China, so it has not been included in medical insurance. Domestic patients may not be able to purchase this drug yet. The German version of the generic version of Nexituzumab available overseas800mg/50ml may cost more than 10,000 yuan per box (the price may fluctuate due to exchange rates), which is relatively expensive. Currently, there are no generic drugs of Nexituzumab on the market. For more drug information and specific prices, please consult Yaode Medical Consultant.
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