Indications for Midostaurin

The main indications of Midostaurin (Midostaurin) include:

1.Acute myeloid leukemia (AML): Midostaurin is used in newly diagnosed adult AML patients, including FLT 3Gene mutation to FLT3-ITD (internal duplication) or FLT3-TKD (tyrosine kinase domain) positive.

2.Kinase-positive systemic mastocytosis (SM-AHN): Midostaurin is used in SM-AHN adult patients, especially those carrying the KIT geneD816V mutation.

3.Ascending myeloid tumors: In addition, midostaurin may be used in the treatment of some ascending myeloid tumors, but the specific use needs to be based on the patient's condition and the doctor's judgment.

Please note that the use of midostaurin should be done under the supervision of a professional doctor and strictly adhere to the doctor's prescriptions and recommendations. Midostaurin should not be used at discretion as it may have a range of side effects and risks. Only a doctor can properly assess a patient's condition and ensure the appropriateness of the medication.

Currently Midostaurin is not available in China, so patients cannot purchase it domestically. Midostaurin abroad is divided into original drugs and generic drugs. The cheaper original version is the Indian version, which costs more than 10,000 yuan. Others include Turkish and European original drugs, which cost tens of thousands to hundreds of thousands, which are relatively expensive. Generic drugs are mainly Indian generic drugs, which cost about several thousand yuan per box. They are much cheaper than the original drug, and the drug ingredients are basically the same as the original drug.