How much does a box of Vemurafenib cost?

Vemurafenib (Vemurafenib) is an oral mutant BRAF-serine-threonine kinase inhibitor. Vemurafenib is a small molecule that interacts as a competitive inhibitor of BRAF mutant species and is particularly effective against the BRAF V600E mutation.

Sincevemurafenib has been approved since 2011 for the treatment of metastatic melanoma harboring a valine BRAF mutation located at codon 600 of exon 15, designated V600E. The V600E mutation, a glutamic acid substitution of valine, accounts for 54% of cutaneous melanoma cases. Vemurafenib's approval was extended in 2017 to treat adult patients with Erdheim-Chester disease whose cancer cells harbor the BRAF V600 mutation. Erdheim-Chester disease is an extremely rare histiocytic disorder that affects the large bones, large blood vessels, central nervous system, skin, and lungs. Erdheim-Chester disease has been reported to be associated with the V600E mutation.

Vemurafenib The original drug has been launched in China and has entered the scope of medical insurance. The price of 240mg*56 tablets per box may be around 7,000 yuan, which is very expensive. The Turkish version of Vemurafenib Original drug listed overseas, specifications240mg*56 tablets, may cost more than 2,000 yuan per box (the price may fluctuate due to exchange rates), which is relatively cheap. There is currently no generic version of Vemurafenib on the market. For more drug information and specific prices, please consult a medical consultant.