How much does a box of Trifluridine Tipiracil Tablets (Lonsurf) cost?

Lonsurf is used to treat cancer of the colon (large intestine) or rectum that has spread to other parts of the body in people who have been treated with other chemotherapy drugs or who cannot be treated with these chemotherapy drugs. It is also used to treat certain types of stomach cancer or cancer located at the junction of the stomach and esophagus (the tube between the throat and stomach) that has spread to other parts of the body in people who have been treated with at least two other chemotherapy drugs.

Trifluridine belongs to a class of drugs called thymidine-based nucleoside analogs, which work by stopping the growth of cancer cells. Tipiracil is a type of drug called a thymidine phosphorylase inhibitor, which works by slowing down the body's breakdown of trifluridine. Trifluridine and tipiracil are available in tablet form to be taken twice daily on certain days of each treatment cycle. Treatment with this drug should be continued as long as the patient is benefiting from it and the side effects are tolerable.

TrifluridineThe original drug of tipiracil tablets has been marketed in China under the trade name Langsif, but it has not yet entered the scope of medical insurance. The price of 15mg*20 tablets per box may be around 6,000 yuan. The price of the Hong Kong version of 15mg*20 tablets per box may be more than 10,000 yuan (the price may fluctuate due to exchange rates).

The Japanese version of trifluridine tipiracil tablets, original drug, specifications 20mg*20 tablets, may be priced around RMB 5,000 per box per box (the price may fluctuate due to exchange rates). There are also cheaper generic versions of trifluridine tipiracil tablets overseas, whose pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of a box of 15mg*20 tablets produced by an Indian pharmaceutical factory may be around RMB 1,000 (the price may fluctuate due to exchange rates).