The Chinese name of Talazoparib

The original drug Talazoparib (Talazoparib) has not yet been launched in China. It may be in the clinical trial stage under the name of Talazoparib Tosylate Capsules. The specific launch time is not yet known, so Talazoparib is not included in the medical insurance. Talazopanib works by blocking the DNA repair activity of a protein called PARP, which binds to altered DNA repair genes, making it harder for cancer cells to survive.

Talazopanib is a poly(ADP-ribose) polymerase inhibitor approved based on theEMBRACA trial for the treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), HER2-negative, locally advanced or metastatic breast cancer (LA/mBC). If possible, breast tumors are surgically removed. But sometimes the tumor has grown too large or the cancer has spread to other parts of the body (metastasized). This is called advanced breast cancer. The combination of talazopanib and enzalutamide is also approved to treat men with prostate cancer that has alterations in a specific set of genes involved in repairing damaged DNA. Enzalutamide works by blocking hormones that stimulate cancer cell growth.

The specifications of Talazopanib original drug marketed overseasThe price of 0.25mg*30 pills per box may be more than RMB 10,000, and the price of 1mg*30 pills per box may be more than RMB 40,000 (the price may fluctuate due to the exchange rate), which is relatively expensive. There are also cheaper generics of talazopanib overseas. For example, the price of a box of 1mg*30 pills produced by a Laos pharmaceutical factory may be more than 3,000 yuan (the price may fluctuate due to the exchange rate).