Can it be completely cured by taking selumetinib?

An investigational drug called selumetinib can shrink tumors in children and young adults with the genetic syndrome neurofibromatosis type 1 (NF1) and may improve symptoms such as pain and decreased mobility caused by tumors called plexiform neurofibromas, which occur in many people with NF1, preliminary results from a clinical trial show.

The phase 2 trial, involving 50 patients ages 2 to 18 with NF1 and plexiform neurofibromas, confirmed the results of a smaller trial that first showed in 2016 that the drug could shrink large tumors. Up to half of people with neurofibromatosis type 1 develop plexiform neurofibromas, which form in nerve cells. Although most of these tumors are not cancerous, they often grow on or under the skin and cause pain and other problems, such as difficulty breathing or walking and disfigurement. Currently, only pediatric oncologists are using selumetinib. The recommended dose is based on the patient's weight and height. The drug is taken twice daily, about 12 hours apart, on an empty stomach. It should not be given to patients who cannot swallow the entire capsule.

SelumetinibThe original drug has been launched in China, but it has not yet entered the scope of medical insurance. SpecificationThe price of 10mg*60 tablets per box may be more than 20,000 yuan, which is relatively expensive. SelumetinibOriginal drug marketed overseas, the price of 10mg*60 pills per box may be more than 50,000 yuan, and the price of 25mg*60 pills per box may be 1 More than RMB 00,000 (the price may fluctuate due to the exchange rate). The ingredients of the original version of selumetinib sold at home and abroad are basically the same. There is currently no generic version of selumetinib on the market. For more drug information and specific prices, please consult Yaode Medical Consultants.