The difference between Sacituzumab govitecan and Trastuzumab

Sacituzumab govitecan and Trastuzumab (Trastuzumab) are two different drugs with some differences in uses and chemical structures. Therefore, their chemical structures are also different, and their specific mechanisms of action are also different.

Gosatuzumab is a new type of antibody drug that treats certain malignant tumors, such as breast cancer and urothelial cancer, by binding to the surface antigenTrop-2. Gosatuzumab consists of an antibody part and a toxin part. The antibody portion recognizes tumor cells by binding to the Trop-2 antigen, while the toxin portion has anti-tumor activity. Trastuzumab is an antibody drug that has been used clinically for many years to treat HER2-positive breast and gastric cancer by binding to the surface antigen HER2. Trastuzumab also contains an antibody part and a toxin part in its structure, but it recognizes tumor cells by binding to the HER2 antigen and releases the toxin part to kill tumor cells.

Gosatuzumab The original drug has been launched in China, but it has not yet been included in the medical insurance. The price of a 100mg bottle may be around 10,000 yuan, which is relatively expensive. Gosatuzumab Original drug marketed overseas has three versions: European version, American version, and Singapore version. SpecificationsThe price of each 100 mg bottle may be around RMB 10,000-35,000 (the price may fluctuate due to exchange rates). The ingredients of gosatuzumab sold domestically and abroad are basically the same. There is currently no generic version of gosatuzumab available on the market. For specific prices and drug information, please consult your medical consultant.