How to take Ribociclib, usage and dosage

The recommended dose of Ribociclib (Ribociclib) is 600 mg (three 200 mg film-coated tablets) once daily for 21 days, followed by 7 days off treatment, resulting in a complete 28-day cycle. Riboxil can be taken with or without food. Riboxiclib is usually used in combination with other drugs. The recommended dosage of the aromatase inhibitor used in combination must be based on its prescribing information; the recommended dosage of combined fulvestrant is 500 mg, administered on days 1, 15, and 29, and once a month thereafter.

Based on current clinical practice standards, premenopausal/perimenopausal women or men treated with reboxil in combination with an aromatase inhibitor and men treated with fulvestrant should be treated with a luteinizing hormone-releasing hormone (LHRH) agonist. If a patient develops symptoms during or after treatment with Ribociclib, the doctor may advise the patient to adjust the dose of Ribociclib, which may include reducing, interrupting, or stopping Ribociclib. The first dose of reboxiclib can be reduced to 400 mg/day (two 200 mg film-coated tablets); the second dose can be reduced to 200 mg/day (one 200 mg film-coated tablet). If further dose reduction below 200 mg/day is necessary, discontinue treatment.

The original drug Riboxil has been launched in China, but due to its short time on the market, its price and purchase methods are not yet known, and it has not yet been included in the scope of medical insurance. The price of the European version of Riboxil's original drug, 200mg*21 tablets, sold overseas may be more than RMB 20,000 per box, while the Indian version of Riboxil's original drug, 200mg*21 tablets, may be priced around RMB 3,000 per box (the price may fluctuate due to exchange rates). The ingredients of the two drugs are basically the same. There are currently no generic versions of Riboxil produced and marketed.