What should Dabigatran etexilate (Pradaxa) not be used with?

Dabigatran etexilate capsule (Pradaxa) is an oral anticoagulant and a direct thrombin inhibitor. When using dabigatran etexilate capsules, patients need to pay attention to some contraindications and interactions with other drugs to ensure the safety and effectiveness of the medication.

1.Antiplatelet drugs: Avoid simultaneous use with antiplatelet drugs such as aspirin, clopidogrel, etc. This is because both antiplatelet drugs and dabigatran etexilate capsules have the effect of inhibiting thrombosis, and their simultaneous use may increase the risk of bleeding.

2.Other anticoagulant drugs: Avoid simultaneous use with other oral anticoagulant drugs such as warfarin (warfarin). Simultaneous use of anticoagulant drugs with different mechanisms may cause excessive anticoagulation of the blood and increase the risk of bleeding.

3.Nonsteroidal anti-inflammatory drugs (NSAIDs): Patients are required to use nonsteroidal anti-inflammatory drugs with caution while taking dabigatran etexilate capsules, as these drugs may increase the risk of bleeding.

4.Benazepril: Benazepril is a commonly used high blood pressure drug, and the simultaneous use of dabigatran etexilate capsules may increase the risk of bleeding. Patients should be monitored by their doctor while using these two drugs.

5.Antifungal drugs: Some antifungal drugs, such as fluconazole, may increase the plasma concentration of dabigatran etexilate capsules and increase the risk of bleeding. Your doctor may need to adjust the dose of dabigatran etexilate while using these medications.

6.PowerfulPglycoprotein inhibitors: Some powerful Pglycoprotein inhibitors, such as aminoglycoside antibiotics, may affect the metabolism of dabigatran etexilate capsules and increase their concentration in the body.

Dabigatran etexilate capsules have been launched in China and have been included in medical insurance. Patients can purchase them domestically. Please consult the local hospital pharmacy for specific prices. Foreign countries mainly use the original drug of dabigatran etexilate capsules, and the cheaper one is the Turkish version of the German original drug, specifications110mg*60The price of 110mg*60 tablets is about three to four hundred, and the ingredients and efficacy are consistent with the original drugs on the market in China.