How much does Ruxolitinib cream cost?

In the United States, Ruxolitinib cream is indicated for the topical treatment of mild to moderate atopic dermatitis and vitiligo. In the EU, ruxolitinib cream is indicated for the treatment of non-segmental vitiligo involving the face in adults and adolescents over 12 years of age. Subsequently, ruxolitinib cream was used as a topical medication to treat vitiligo in the United States. It was the first drug treatment for pigmentation in patients with vitiligo approved by the U.S. Food and Drug Administration (FDA).

Ruxolitinib cream is a white to off-white oil-in-water, soluble topical emulsion. Each ruxolitinib cream contains 15 mg of ruxolitinib (equivalent to 19.8 mg of ruxolitinib phosphate). Ruxolitinib phosphate is a Janus kinase inhibitor that inhibits JAK1 and JAK2. JAK2 mediates signaling of many cytokines and growth factors important for hematopoiesis and immune function. It is unclear how inhibition of specific JAK enzymes correlates with therapeutic efficacy.

The original drug of ruxolitinib cream has not yet been marketed in China, so it cannot be included in medical insurance. The price of ruxolitinib cream Original drug, specificationsinn 1.5%*60g, which is marketed overseas, is around RMB 20,000 per tube (the price may fluctuate due to the exchange rate), which is relatively expensive. The price of generic ruxolitinib cream marketed overseas is relatively cheap, and its pharmaceutical ingredients are basically the same as those of the original drug. The price of the specificationinn 1.5%*30g produced by a Bangladesh pharmaceutical factory is around 600 yuan per tube (the price may fluctuate due to exchange rate effects).