What does dimethyl fumarate (Tecfidera) do?

Dimethyl fumarate (Tecfidera) is an oral drug for the treatment of multiple sclerosis (Multiple Sclerosis, MS). Its main ingredient is dimethyl fumarate. Multiple sclerosis is a chronic inflammatory disease of the central nervous system that usually manifests as neuronal demyelination and neuronal damage, leading to a series of neurological disorders.

The main role of dimethyl fumarate is to slow the progression and worsening of symptoms of multiple sclerosis by modulating the immune system's response. Its exact mechanism of action has not been fully elucidated, but the current theory is that dimethyl fumarate affects the activity of immune cells and reduces inflammatory responses, thereby reducing the degree of damage to the nervous system.

Dimethyl fumarate is thought to have multiple implications for the treatment of multiple sclerosis. First, it may reduce the activity of immune cells and inhibit their attack on the central nervous system, thus slowing the progression of the disease. Second, dimethyl fumarate may reduce the inflammatory response and help reduce the rate at which neurons lose myelination. Finally, by affecting the balance of the immune system, dimethyl fumarate may help relieve various symptoms that people with multiple sclerosis often face, such as sensory impairment, movement problems, and fatigue.

In general, the role of dimethyl fumarate is to slow down the development of multiple sclerosis and improve the quality of life of patients by regulating the immune system. However, patients should closely monitor the side effects when using this drug and conduct treatment under the guidance of a doctor to ensure safe and effective use.

The original drug of dimethyl fumarate has been launched in China and has been included in medical insurance. Patients can buy it domestically at a price of about 5,000 to 6,000 yuan. Please consult the local hospital pharmacy for specific prices. The main foreign drug is dimethyl fumarate original drug. The cheaper one is the Indian original drug, which costs more than 2,000 yuan and has the same composition and efficacy as the domestic original drug.