How much does a box of Enasidenib cost?

Enasidenib (Enasidenib) is approved for patients with acute myeloid leukemia (AML) caused by mutations in the IDH2 gene. About 15% of patients with acute myeloid leukemia have this mutation, IDH2 mutations and mutations in a related gene, IDH1, are found in other types of leukemia as well as myelodysplastic syndromes, glioblastoma and cholangiocarcinoma. Proteins made from mutated IDH genes can drive cells to become cancerous.

Ensidipine is the first-of-its-kind oral targeted mutantIDH2 inhibitor, Results from a phase I/II single-arm study of ensidipine in patients with advanced hematological malignancies withIDH2 mutations The results showed that after at least 6 months of treatment, 19% of patients experienced complete remission at a median time of 8.2 months, and 4% experienced complete remission with partial recovery of blood cell counts at a median time of 9.6 months. Common side effects of ensidipine include nausea, vomiting, diarrhea, increased levels of bilirubin (a substance in bile), and decreased appetite.

Ensiidi plain investigational medicine is not currently on the market in the country, nor is it covered by medical insurance. The price of ensiidi plain research medicine when it is launched overseas is very high. The price of each box may be around 30,000 yuan (the price may fluctuate due to the exchange rate). The expensive price may increase the pressure on families with heavy financial burdens. Currently, there are cheaper generic encidipine drugs produced by other pharmaceutical companies overseas. For example, the price of Specification50mg*60 tablets produced by a Bangladesh pharmaceutical factory may be around 4,000 yuan per box (the price may fluctuate due to exchange rates). Its drug ingredients are basically the same as those of the original encidipine generic drug. For more drug information and specific prices, please consult Yaode Medical Consultant.