How many days does one bottle of Enasidenib last?

Enasidenib (Enasidenib) is a new oral small molecule IHD2 inhibitor. It is a non-cytotoxic differentiating agent that acts by inducing the maturation of malignant cells. Similar to all-trans retinoic acid (ATRA) used to treat acute promyelocytic leukemia (APML), ensidipine induces terminal differentiation of leukemic myeloblasts and restores normal trilineage hematopoiesis in responding patients without evidence of apoptosis. This unique differentiation therapeutic effect aids in the reconstitution of the immune system and the restoration of normal function, thus providing an additional advantage over traditional cytotoxic treatments.

Ensidipine targets a specific gene mutation calledIDH2, which affects the bone marrow. Ensidipine is used to treat acute myeloid leukemia in adults with IDH2 mutations. Ensidipine is used when acute myeloid leukemia has relapsed or has not improved with previous therapy. Ensidipine Common specifications are50mg*30 and 100mg*30. The recommended dosage is 100mg once a day. One bottle can be taken for about half a month to a month.

Ensiidi plain investigational medicine is not currently on the market in the country, nor is it covered by medical insurance. The price of ensidipine plain medicine when it is launched overseas is very high, and the price of each box may be around 30,000 yuan (the price may fluctuate due to the exchange rate). Currently, there are cheaper generic encidipine drugs produced by other pharmaceutical companies overseas. For example, the price of Specification50mg*60 tablets produced by a Bangladesh pharmaceutical factory may be around 4,000 yuan per box (the price may fluctuate due to exchange rates). Its drug ingredients are basically the same as those of the original encidipine generic drug.