How long does Erdafitinib treatment take to take effect?

Erdafitinib, a pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, demonstrated clinical activity and tolerability in a preliminary analysis of the BLC2001 study in patients with advanced urothelial cancer and prespecified FGFR alterations at a median follow-up of 11 months. However, the time it takes for the drug to take effect varies from individual to individual, depending on the patient's condition and physical condition.

The results showed that at a median follow-up of 24.0 months and a median treatment duration of 5.4 months, the objective response rate (ORR) of patients treated with the erdafitinib regimen was 40%. These findings proved to be consistent with the ORR reported in the trial's preliminary analysis, which was 40%. Based on clinical trial results, erdafitinib typically begins to show efficacy within weeks of starting treatment. However, this does not mean that every patient will see improvement in the same amount of time. Some patients may feel the effects within a few weeks, while others may take longer to see significant improvement.

The original version of erdafitinib has not yet been launched in China, so it cannot be covered by medical insurance. The original version of erdafitinib currently sold in Hong Kong may cost more than 20,000 yuan per box of specifications 4mg*14 tablets (the price may fluctuate due to exchange rates). Cheaper erdafitinib generic drugs produced by other pharmaceutical factories are also sold overseas. The pharmaceutical ingredients are basically the same as those of the original drug. For example, the price of 4mg*60 tablets produced by a Bangladeshi pharmaceutical factory may be more than 3,000 yuan per box (the price may fluctuate due to exchange rates).