How to use Alpelisib-Piqray

Alpelisib (Alpelisib) - PiqrayThe recommended dose is 300 mg (two film-coated tablets) once daily (two 150 mg film-coated tablets), taken with food, and treatment is continued until disease progression or unacceptable toxicity occurs. The recommended dose of fulvestrant when administered with apelvis is 500 mg on days 1, 15 and 29 and monthly thereafter, subject to adjustment based on its prescribing information.

If the patient is taking Apelvis, and is unable to swallow the tablets whole, they may be dissolved in water. Place the tablets in a drinking glass containing 2-4 ounces (60-120mL) of water. Wait 5 minutes, then crush the tablets and stir the mixture with a spoon. Drink the mixture immediately. Add another 2 to 3 tablespoons of water to the glass and stir with the same spoon to rinse out any remaining particles in the glass. Drink all of this mixture to ensure you receive all of the medication, repeating as necessary.

If a patient develops an adverse reaction during treatment with Apelvis, the doctor will adjust the dose according to the severity. The first dose will be reduced to 250 mg once daily (one 200 mg tablet and one 50 mg tablet), and the second dose will be reduced to 200 mg once daily (one 200 mg tablet). If the second dose reduction is intolerable, please permanently discontinue Apelvis.

The original drug of Apellis is not marketed in the country and therefore cannot be included in medical insurance. There are European and Indian versions of the original Apelvis drug sold overseas. The ingredients are basically the same. The price of the European version of 150mg*56 tablets per box may be more than 4 RMB 40,000 ( (The price may fluctuate due to the exchange rate), The price of the Indian version150mg*28 tablets per box may be more than 5,000 yuan (the price may fluctuate due to the exchange rate). There are currently no generic versions of Apelvis produced and marketed.