How long does it take for Alpelisib-Piqray to work?

Alpelisib (Alpelisib)-Piqray is a drug that targets the PI3K enzyme and is used to treat certain hormone receptor-positive, HER2-negative advanced breast cancers. Apelvis works by targeting breast cancer cells that have changes (mutations) in a gene called PIK3CA. In breast cancers with mutations in the PIK3CA gene, a protein called PI3K is involved in helping cancer cells reproduce and grow. By blocking the action of PI3K, Apelix helps stop cancer from growing and spreading.

How long a drug takes to work varies among individuals and depends on many factors, including severity of illness, individual metabolism, and other factors that may affect drug metabolism. Based on the results of clinical trials, it usually takes a while for Apelvis to show therapeutic effects. In a clinical trial of patients with advanced breast cancer, approximately 30% of patients experienced tumor shrinkage after 4 months of taking Apelvis. However, everyone may respond differently, and some people may see the effects of treatment earlier or later.

The original drug of Apellis is not marketed in the country and therefore cannot be included in medical insurance. There are European and Indian versions of the original Apelvis drug sold overseas. The ingredients are basically the same. The price of the European version of 150mg*56 tablets per box may be more than 4 RMB 40,000 ( (The price may fluctuate due to the exchange rate), The price of the Indian version150mg*28 tablets per box may be more than 5,000 yuan (the price may fluctuate due to the exchange rate). There are currently no generic versions of Apelvis produced and marketed.