What are the side effects of Vigabatrin?

In clinical studies of Vigabatrin (Vigabatrin), the most common (≥5%) adverse reactions were headache, drowsiness, fatigue, dizziness, convulsions, nasopharyngitis, weight gain, upper respiratory tract infection, visual field defects, depression, tremor, nystagmus, nausea, diarrhea, memory impairment, insomnia, irritability, abnormal coordination, blurred vision, double vision, vomiting, influenza, fever and rash.

After Vibatrin was put on the market, birth defects, deafness, delayed puberty, gastrointestinal bleeding, esophagitis, developmental delay, facial edema, malignant hyperthermia, multiple organ failure, cholestasis, myotonia, encephalopathy, hypertonia, hypotonia, muscle spasm, myoclonus, optic neuritis, movement disorders, acute psychosis, and apathy , delirium, hypomania, neonatal restlessness, mental disorder, laryngeal edema, pulmonary embolism, respiratory failure, stridor, angioedema, maculopapular rash, pruritus, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), alopecia and other adverse events.

The original Vigabatrin drug has not yet been launched in China, so it is not included in medical insurance. The Hong Kong version of the specificationsThe price of 500mg*100 bags per box may be more than 1,000 yuan (the price may fluctuate due to exchange rate effects). It is reported that an Indian chemical generic drug vigabatrin powder is on the domestic market. The price of each box of 500mg*50 bags may be more than 3,000 yuan. Its pharmaceutical ingredients are basically the same as those of the original drug. The Turkish version of Vigabatrin currently sold overseas may cost more than RMB 1,000 per box of 500mg*100 bags (the price may fluctuate due to exchange rates).