How much does a box of Vigabatrin cost?

Vigabatrin (Vigabatrin) is commercially available in the form of tablets and oral solutions. The tablets are indicated for the adjunctive treatment of adults with complex partial epilepsy refractory to multiple treatments. The oral solution is approved as the only drug in the United States for patients with infantile spasms. Its chemical name is (±)4-amino-5-hexenoic acid.

Seizures are caused by abnormal electrical interference in the brain, and there are several types of seizures, including complex partial seizures, which occur in more than one-third of all cases, and infantile spasms, which typically occur in a baby's first year of life and are a component of Wester's syndrome, which typically affects patients between 4 and 8 months of age. Vigabatrin's mechanism of anticonvulsant action stems from its ability to inhibit gamma-aminobutyric acid transaminase (GABA-T), the enzyme responsible for the metabolism of the inhibitory neurotransmitter GABA. This step leads to an increase in GABA levels in brain synapses. Epilepsy is thought to be caused by low levels of GABA in the central nervous system (CNS).

The original Vigabatrin drug has not yet been launched in China, so it is not included in medical insurance. The Hong Kong version of the specificationsThe price of 500mg*100 bags per box may be more than 1,000 yuan (the price may fluctuate due to exchange rate effects). It is reported that an Indian chemical generic drug vigabatrin powder is on the domestic market. The price of each box of 500mg*50 bags may be more than 3,000 yuan. Its pharmaceutical ingredients are basically the same as those of the original drug. The Turkish version of Vigabatrin currently sold overseas may cost more than RMB 1,000 per box of 500mg*100 bags (the price may fluctuate due to exchange rates).