Pirfenidone Price 2023

Pirfenidone (Pirfenidone) is an oral anti-inflammatory and anti-fibrotic drug used to treat idiopathic pulmonary fibrosis. It is a low molecular weight phenyl-substituted pyridone with antifibrotic activity in vitro and in vivo. In animal models, pirfenidone reduces fibroblast proliferation, transforming growth factor-β (TGF-β) synthesis and activation of fibrotic pathways.

In several prospective placebo-controlled trials, pirfenidone was found to reduce fibrosis progression and worsening of lung function in patients with idiopathic pulmonary fibrosis. Pirfenidone was approved for use in the United States in 2014, but has been available in other countries for much longer. It is sold in 267 mg capsules under the trade name Esbriet. The typical initial dose for adults is one capsule (267 mg) taken three times daily, which may be increased to three capsules taken three times daily based on tolerance. Side effects are not uncommon but are usually mild and can include photosensitivity, rash, and gastrointestinal discomfort, along with nausea, diarrhea, indigestion, reflux, and abdominal pain.

The original drug pirfenidone has been approved for marketing in China and has entered the scope of Class B medical insurance. Reimbursement is limited to patients who meet the indications. SpecificationsThe price of each box of 100mg*54 tablets is about 500 yuan. There are also generic pirfenidone drugs produced in other countries overseas. For example, the price of a box of 200mg*30 tablets produced by an Indian pharmaceutical factory is around RMB 100 (the price may fluctuate due to the exchange rate). The ingredients of the generic drugs are basically the same as those of the original drug. For more drug information and specific prices, please consult Yaode Medical Consultant.