Is there a generic version of Tepotinib? What is the price?

It is understood that generic drugs of Tepotinib have been produced and put on the market. The ingredients of these generic drugs are basically the same as those of the original Tepotinib drug, but there are differences in manufacturers, production specifications, prices, etc., and they are currently purchased overseas. To buy generic Tepotinib, the common manufacturer is Laos ASEAN Pharmaceuticals. Specifications The price of 225mg*60 tablets per box may be more than 8,000 RMB (the price may fluctuate due to the exchange rate).

The original drug of Tepotinib is an oral MET inhibitor for the treatment of advanced non-small cell lung cancer. It can inhibit the carcinogenicMET receptor signaling caused by MET (gene) changes. It was discovered and developed internally by Merck in Germany. It has a highly selective mechanism of action and may improve the prognosis of aggressive tumors with poor prognosis and these specific changes. Tepotinib is also in combination with osimertinib in the Phase II INSIGHT 2 study in patients with MET-amplified, advanced or metastatic non-small cell lung cancer (with activating EGFR mutations) who have progressed after first-line treatment with osimertinib, and in combination with cetuximab in a Phase II prospective study in patients with RAS/BRAF wild-type left-sided metastatic colorectal cancer who are resistant to anti-EGFR antibody-targeted therapy due to MET amplification.

The original drug Tepotinib has been launched in China, but it is not yet eligible for medical insurance. Because it has been on the market for a very short time in China, it cannot yet be purchased in domestic hospitals or pharmacies. Tepotinib Original drug currently on the market overseas is relatively expensive. SpecificationThe price of 225mg*30 tablets per box may be around RMB 80,000 (the price may fluctuate due to the exchange rate). For specific prices and drug details, please consult Yaode’s medical consultant.