How long do the side effects of Crizotinib (Crizotinib) targeted drug last?

Crizotinib (Crizotinib) is now one of several TKIs approved by the U.S. Food and Drug Administration (FDA) for the treatment of ALK-mutant non-small cell lung cancer. As a targeted drug, it has some possible side effects. The duration of these side effects varies from person to person and depends on the patient's medical condition and individual differences.

The most common adverse reactions in patients with non-small cell lung cancer are visual disturbance, nausea, diarrhea, vomiting, edema, constipation, elevated transaminase, fatigue, decreased appetite, upper respiratory tract infection, dizziness and neuropathy. These discomforts may appear at the beginning of treatment and gradually reduce or disappear over time. For most patients, these side effects usually resolve within a few weeks or months. However, some patients may experience longer-lasting side effects that may even require monitoring and management throughout treatment. Each patient's situation is unique, so it's best to work closely with your doctor to regularly evaluate side effects and adjust treatment as needed.

The original drug Crizotinib has been launched in China and is covered by medical insurance, but it is only reimbursed for patients who meet the indications. The price per box may be around RMB 15,000. The price of the original Turkish version of Crizotinib sold overseas may be more than RMB 10,000 per box (the price may fluctuate due to exchange rates), which is expensive. There are also cheaper generic crizotinib drugs available overseas. The ingredients are basically similar to those of the original drugs sold domestically and abroad. For example, the price of 250mg*60 tablets produced by a Bangladesh pharmaceutical factory may be more than 2,000 yuan per box (the price may fluctuate due to exchange rates).