How many boxes of Crizotinib should be taken a month?

Crizotinib treats three types of genetically mutated cancers: non-small cell lung cancer (NSCLC), anaplastic large cell lymphoma (ALCL), a blood cancer, and anaplastic lymphoma kinase (ALK)-positive inflammatory myofibroblastic tumor (IMT), a solid tumor that can occur in the lungs, abdomen, or pelvic area. Crizotinib blocks the activity of the protein in tumors with genetic alterations. This effect helps cancer grow and spread.

Crizotinib is an oral prescription drug produced by Pfizer. It is usually taken as a capsule or oral granules twice daily, but different doses may be required. Some doses may be based on the patient's weight. Be sure to follow your doctor's instructions exactly. The common dosage of crizotinib is 250 mg * 60 tablets. If used to treat non-small cell lung cancer, the dosage for adults is 250 mg orally twice daily. It is estimated that patients need to take about one box a month, provided that the patient does not experience other adverse events that cause the drug to be reduced or interrupted during use.

The original drug Crizotinib has been launched in China and is covered by medical insurance, but it is only reimbursed for patients who meet the indications. The price per box may be around RMB 15,000. The price of the original Turkish version of Crizotinib sold overseas may be more than RMB 10,000 per box (the price may fluctuate due to exchange rates), which is expensive. There are also cheaper generic crizotinib drugs available overseas. The ingredients are basically similar to those of the original drugs sold domestically and abroad. For example, the price of 250mg*60 tablets produced by a Bangladesh pharmaceutical factory may be more than 2,000 yuan per box (the price may fluctuate due to exchange rates).