Can mitotane be purchased in the country?

Mitotane is an oral adrenotoxic agent. The chemical name is ()-1, 1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane(also known as o, p′-DDD). Mitotane was first marketed in 1964 and was approved by the US FDA for adrenocortical cancer in 1970. Mitotane was finally approved for marketing in China 53 years after it was launched in Europe and the United States. On 20239month8, it was approved for marketing by the China National Medical Products Administration for the treatment of adrenocortical cancer. Mitotane has just been approved for sale in China. It is currently not available in China. It is understood that it may be available in China in about two to three months.

If patients need mitotane, they can contact overseas medical consulting agencies and purchase the overseas version through domestic formal and legal channels. This medicine is available in Hong Kong and Laos. Hong Kong is the original drug and the European version. The retail price in pharmacies is about 8,000 to 9,000 for 500 mg and 100 tablets. Generic drugs can be purchased from Laos, and the version officially marketed in Laos has government approval. The retail price of 100 tablets of 500mg in Laos is about 3,000. Patients can choose drug versions based on their financial situation.

Mitotan is an adrenal cytotoxic agent with an unknown mechanism of action. Mitotane alters the peripheral metabolism of steroids and directly inhibits the adrenocortex. A decrease in 17-hydroxycorticosteroids and an increase in the formation of 6-β-hydroxycortisol have been reported without a decrease in corticosteroid concentrations. If you want to get more high-quality information, you can contact Yaode. Yade will do its best to learn more about high-quality overseas drugs for you.

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