What kind of lung cancer does Crizotinib treat?

CrizotinibTreats three types of genetically mutated cancers: ALK+ or ROS1+< span>mutated non-small cell lung cancer, as well as anaplastic large cell lymphoma(ALK+), and ALK+inflammatory myofibroblastic tumor(IMT). Crizotinib blocks the activity of proteins in tumors with genetic changes, an effect that helps the cancer grow and spread. Crizotinib is an oral prescription drug produced by Pfizer. It is usually taken as one capsule twice a day. The specific medication should be taken according to the doctor's advice.

Crizotinib is used to treat adult patients with metastatic non-small cell lung cancer (NSCLC) due to a genetic defect. Metastasis means the cancer has spread to other parts of the body. These Type 1 lung tumors are caused by defects in the anaplastic lymphoma kinase (ALK) gene or the ROS1 gene. These mutations cause cells to multiply and grow out of control. Approximately 1% to 7% of patients with non-small cell lung cancer have ALK gene mutations, and most patients do not smoke. ROS-1gene alterations occur in approximately 1% of patients with non-small cell lung cancer.

Crizotinib is also approved for the treatment of systemic anaplastic large cell lymphoma (ALCL) in children 1 year and older and those with ALK+ Young people are used when their cancer comes back or when previous treatments have not worked or are no longer working (refractory). ALCLis a rare type of non-Hodgkin lymphoma. Lymphoma is a cancer of the lymphatic system, which is part of the immune system. It occurs due to abnormal growth of white blood cells used to fight infection. Approximately 90% of ALCL cases in young people are ALK positive.

In July 2022, the FDA approved crizotinib for the treatment of adults and children 1 years old. Anaplastic lymphoma kinase (ALK) positive inflammatory myofibroblastic tumor (IMT) in children and older who cannot be surgically removed, have recurred, or have failed other treatments. IMT is a rare cancer that is composed of various types of cells, such as smooth muscle cells, connective tissue cells or immune cells. It usually appears in the lungs, abdomen (stomach area) or pelvis, but can occur anywhere in the body. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to learn more about high-quality overseas drugs for you.

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