How many years can you live taking Crizotinib?

Crizotinib is a first-generation targeted drug used to treat ALK+ or ROS1+ mutations Non-small cell lung cancer, as well as anaplastic large cell lymphoma(ALK+), and ALK+inflammatory myofibroblastic tumor(IMT). How many years can you survive taking crizotinib?

The survival rate of patients varies depending on their condition and treatment. For patients with ALK+ or ROS1+ mutated non-small cell lung cancer, in clinical studies, patients who received crizotinib capsulesALK+< /span>The time that lung cancer did not worsen was 7 months, compared with 10.9 months for patients who received chemotherapy infusion, and ROS1+ Among patients with NSCLC, the average duration of treatment with crizotinib was 18.3 months. For patients with anaplastic large cell lymphoma(ALK+), in 26casesALK+anaplastic large cell lymphoma(ALCL )In clinical studies of patients, 88% of patients responded to crizotinib treatment. Among 23 patients who responded, 5 patients (22%)Responses remained 12 months after starting treatment, 9 patients (39%) Responses were maintained at 6 months, and 13 patients (57%) maintained responses at 3 months. For ALK+inflammatory myofibroblastic tumor(IMT)patients, including 14 children andIn the study of 7 adults, 12 of 14 children (86%) experienced an objective response, which was the primary endpoint. Out of 7 adults, 5 had objective reactions, and 12 children Of 5 and 7 of 1 adults had a complete response. An objective response means that the tumor has shrunk partially or completely, but does not mean that the cancer has been cured. In children, duration of response (DOR) was found to be 6 months or longer in 7 patients and 12 months or longer in 7 patients. In adults, all 5 patients had a DOR of 6 months or longer,2 patients had DOR of 12 months or longer for ALKS+ IMTwas treated with crizotinib until disease progression or unacceptable toxicity.

If you have moderate to severe liver disease, severe kidney disease, experience certain serious side effects, or take certain types of medications (called potentCYP3Ainhibitors), your doctor may need to adjust your dose or frequency of medication. If you experience serious adverse reactions, your doctor may decide you need to stop treatment temporarily or permanently. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to learn more about high-quality overseas drugs for you.