How long does resistance to Bedaquiline last? What to do after drug resistance?

Bedaquiline (Bedaquiline) is a multi-drug-resistant tuberculosis drug. In 2012 Bedaquiline was approved by the United StatesFDA was approved for marketing, and bedaquiline was launched in China on January 2020. Bedaquiline is used with other medicines to treat tuberculosis that is resistant to other antibacterial drugs. Bedaquiline is indicated in adults and children who are at least 5 years old and weigh at least 15kg.

Relevant data show that widespread and widespread bedaquiline resistance has not yet been discovered. Drug resistance is related to the patient's condition and personal constitution. If bedaquiline is resistant, other treatment options should be adopted according to the doctor's advice, usually a combination treatment plan that combines a variety of effective anti-tuberculosis drugs to increase the effectiveness of treatment. If resistance occurs, patients are asked to contact their doctor immediately.

Bedaquiline (Bedaquiline) is a new anti-tuberculosis drug with significant minimum inhibitory concentrations (MICs) for both drug-sensitive and drug-resistant tuberculosis. Tuberculosis is now the world's largest infectious disease killer, Although the estimated incidence of TB has declined slightly over the past few years, it remains out of control in some regions, including Africa. The emergence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has the potential to further undermine control in several regions of the world. Drug-resistant TB poses a significant threat as it underlies nearly 25% of TB mortality worldwide, is associated with high morbidity, poses a threat to health care workers, and makes treatment unsustainably expensive. The emergence of highly drug-resistant tuberculosis, as well as bacterial resistance to new drugs, has caused further concern.

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