When was Bedaquiline launched on the market? Is it covered by medical insurance?

Bedaquiline (Bedaquiline) is produced by Johnson & Johnson Pharmaceuticals in the United States. It is a multi-drug-resistant anti-tuberculosis drug used in 3-drug combination regimens including pretomanid and linezolid to treat extensive drug resistance(XDR)Pulmonary tuberculosisMDRpulmonary tuberculosis caused by Mycobacterium tuberculosis that is resistant to isoniazid, rifampicin, any fluoroquinolone, and at least one injectable antituberculosis drug)or is intolerant or unresponsive to treatment.

Bedaquiline was approved for marketing by the U.S.FDA in 2012 and in 2020< span>1month2day Bedaquiline was launched in China. At present, bedaquiline has been included in the domestic Class B medical insurance reimbursement drugs. The price in domestic pharmacies is around 100mg24 tablets5000, which is relatively expensive. This medicine is also available in Russia. The price in Russian hospitals is around 100 mg, 180 tablets, 1,560, which is relatively favorable. Patients can choose drug versions based on their financial situation. The bedaquiline-pretomanid-linezolid regimen is 90% effective against highly drug-resistant tuberculosis, but the incidence of adverse events is high when 1200 mg linezolid is taken daily. In one clinical trial, patients who received bedaquiline had an increased risk of death compared with patients who received placebo (11.4% and 2.5%, respectively). Use bedaquiline only when effective treatment options for MDR-TB are not otherwise available. Prolongation of the QT interval may occur during use of bedaquiline, and concomitant use with other drugs associated with prolongation of the QT interval may have additive effects on the QT interval. Monitor the ECG and discontinue bedaquiline if clinically important ventricular arrhythmias or QT occurc occur F >500Milliseconds(Confirmed by repeat ECG). If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to help you learn more about high-quality overseas drugs.