How long does it take to stop taking Bedaquiline?

Bedaquiline is an antituberculosis agent used with other drugs to treat tuberculosis that is resistant to other antibacterial drugs. Bedaquiline is indicated for adults and children who are at least 5 years old and weigh at least 15 kg.

The recommended dosage of bedaquiline in the instructions is 1 week and 2 week, 400 mg orally per day. Week 3 to week 24, 3 times per weekorally 200 mg, with an interval of at least 48 hours between two doses, and a duration of treatment of 24 weeks. Therefore, bedaquiline can be discontinued after taking it for 24 weeks.

Data on the use of bedaquiline in pregnant women are insufficient to determine whether there is a risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes associated with the drug. In animal studies(rats and rabbits)receiving the drug at approximately 6 times the recommended dose, no adverse embryotoxicity was observed. Pregnant women are at increased risk for complications of active tuberculosis, which may result in adverse maternal and neonatal reactions (e.g., maternal anemia, cesarean section, prematurity, low birth weight, birth asphyxia, perinatal infant death). It is not known whether it distributes into breast milk, affects milk production, or has effects on breastfed infants. Distributed in mouse milk. Consider the benefits of breastfeeding and the importance of bedaquiline to women, as well as the potential adverse effects of the drug or underlying maternal disease on the breastfed child. Safety and efficacy have not been established in patients aged < 5 years or weighing < 15 kg. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to help you learn more about high-quality overseas drugs.

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