Can bedaquilin be used alone?

Bedaquilineis ananti-tuberculosis drug used in: >Pretomanid3 drug combination regimen, including pretomanidand linezolid, for the treatment of extensive drug resistance(XD R)Tuberculosis(That is, meter (abbreviation of meter)) Pulmonary tuberculosis is very sensitive to isoniazid, Fupin, any fluoroquinolone, and at least one injectable antituberculosis drug-resistant)or treatment-intolerant or unresponsiveMDRpulmonary tuberculosis. Bedaquiline cannot be used alone in the treatment of pulmonary tuberculosis. It must be used in combination with other anti-tuberculosis drugs. Bedaquiline was released in2020year1month2 was launched in China on the 1st. At present, bedaquiline has been included in the domestic Class B medical insurance reimbursement drugs. The specification of bedaquiline on the domestic market is 100mg*188 tablets. The price is 37600yuan per box, about 2 million after medical insurance There are many. There is currently a Russian version of this medicine. The price in Russian hospitals is around 100mg, 188 tablets, 1 about 15,000 and 56,000. The cost is more favorable, and patients can choose the drug version according to their own financial situation.

In a placebo-controlled clinical trial, adults treated with bedaquiline had an increased risk of death (11.4% vs. 2.5%, based on data at week 120) . The reason for the increased risk of death is unknown. There was no correlation between death and sputum culture conversion, relapse, susceptibility to other antituberculosis drugs, HIV status, or disease severity. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to learn more about high-quality overseas drugs for you.