When do the side effects of dabrafenib occur?

Dabrafenib (Dabrafenib) is a targeted therapy drug used to treat malignant tumors with BRAF V600E or V600K mutations, such as melanoma and non-small cell lung cancer. The use of dabrafenib may cause some side effects. The onset time of these side effects will vary depending on individual differences and can generally be divided into early and late side effects.

Early side effects usually occur within a few weeks of starting treatment and may include fever, fatigue, and headache, possibly due to activation of the immune system during treatment. Skin reactions including rash, dryness, itching, redness, etc. may also occur. Late side effects often occur after long-term use of dabrafenib and may include arrhythmias and heart problems, vision problems including blurred vision, dry eyes, and eye tingling, elevated liver enzymes, liver function abnormalities such as jaundice, bleeding, and clotting problems. Each person's reaction and side effects to dabrafenib may be different. If patients are taking dabrafenib, it is recommended to pay close attention to their physical condition and promptly inform their doctor of any discomfort or side effects.

The original drug of dabrafenib is relatively expensive and has been covered by medical insurance since it was launched in China. Currently only eligible patients are reimbursed. The price of each box of 50mg*120 capsules may be around around 10,000. The Turkish version of the original drug Dabrafenib sold overseas, Specifications 75mg*120 capsules, may cost around 10,000 per box (the price may fluctuate due to exchange rates). There are also relatively cheap generics of dabrafenib sold overseas, and their pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, Specifications produced by Laos Pharmaceutical Factory The price of 75mg*120 tablets per box may be more than 4,000 yuan (the price may fluctuate due to exchange rates).