How much does Selumetinib cost?

SelumetinibIs a multi-kinase inhibitor. Selumetinib is used to treat patients with plexiform neurofibromas that cannot be surgically removed2Type 1Neurofibromatosis(NF1) in children aged > years and older.

Selumetinib was developed by AstraZeneca. Selumetinib was released in2023 year4 month It will be launched in China on the 28th. The retail price in domestic pharmacies is about 10mg60 tablets23600 yuan. There are original research versions overseas, with retail prices of around 50,000 for 10mg 60 tablets and 145,000 for 25mg 60 tablets. Patients can choose the drug version according to their own financial situation.

SelumetinibCommon side effects are headache, nausea, vomiting, abdominal pain, diarrhea, and fatigue, Musculoskeletal pain(Body pain affecting bones, muscles, ligaments, tendons, and nerves), fever, dry skin, acneiform rash(Acne)and other rashes, Stomatitis(Inflammation of the mouth and lips), paronychia(Infection of the skin around toenails or fingernails)and itching etc. Because selumetinib is thought to be metabolized by the hepatic enzymes CYP3A4 and CYP2C19, patients taking selumetinib are discouraged from using it Use moderate to severe CYP3A4inhibitors (such as grapefruit juice) and CYP2C19Inhibitor fluconazole. Selumetinib is a kinase inhibitor, more specifically, a selective inhibitor of mitogen-activated protein kinase kinase kinase (MAPK kinase or MEK) isoforms 1 and 2. These enzymes are part of the MAPK/ERK pathway, which regulates cell proliferation (growth and division) and are overactive in many types of cancer. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to learn more about high-quality overseas drugs for you.