What are the generic drugs of Trametinib tablets?

The original drug Trametinib (Trametinib) is already on the market in many countries and is a kinase inhibitor. It is understood that there are currently many countries producing generic trametinib drugs overseas. Its pharmaceutical ingredients are basically the same as those of the original drug. It is suitable for the treatment of melanoma, non-small cell lung cancer, thyroid cancer, solid tumors and low-grade gliomas with BRAF V600 mutations. There may be slight differences in production specifications and prices. Common manufacturers of generic drugs include Laos Second Pharmaceutical Factory, Lucius Pharmaceuticals, etc.

Trametinib is often provided in the form of trametinib tablets for oral administration, available in specifications of 0.5 mg and 2 mg tablets. Depending on its indications, patients can take trametinib tablets once a day at least 1 hour before a meal or at least 2 hours after a meal. Common adverse reactions to trametinib as a single agent include rash, diarrhea, and lymphedema. Warnings and precautions related to trametinib include new primary malignancies, bleeding, colitis and gastrointestinal perforation, venous thromboembolism, cardiomyopathy, ocular toxicity, interstitial lung (ILD), serious febrile reactions, serious cutaneous toxicity, hyperglycemia, and embryo-fetal toxicity.

The original drug of Trametinib has been launched in China and is included in the scope of medical insurance, but it may only be available to patients who meet the indications. The price of 2 mg*30 tablets is more than RMB 10,000. The original drug of Trametinib sold overseas, with the price of 2 mg*30 tablets, is more than RMB 7,000 (the price may fluctuate due to exchange rates). Currently, the price of 2mg*30 tablets of generic drugs produced by Laos pharmaceutical factories is more than RMB 2,000 (the price may fluctuate due to the exchange rate). For specific drug prices and drug information, please consult Yaode Medical Consultant.