Is the recurrence rate after cure with bedaquiline acceptable?

Bedaquiline (Bedaquiline) is a drug used to treat multidrug-resistant tuberculosis. It can effectively reduce the disease and improve the cure rate during treatment. However, relapse is a common problem in TB treatment, not only with bedaquiline but also with other anti-TB drugs. Although bedaquiline can significantly reduce the risk of recurrence, completely eliminating the possibility of recurrence is difficult.

For patients with multidrug-resistant TB, bedaquiline is often given in combination with other anti-TB drugs, which improves cure rates and reduces the risk of relapse. However, even with comprehensive and effective treatment, there is still a certain risk of recurrence. Some clinical studies have shown that most MDR-TB patients remain relapse-free for 5 years after successful treatment Although relapse is a problem that cannot be ignored, bedaquiline's achievements in treating tuberculosis are remarkable. For patients with multidrug-resistant tuberculosis, using bedaquiline as part of a treatment regimen can improve cure rates and delay or reduce the chance of relapse.

The drug is marketed in China as bedaquiline fumarate tablets and has been included in the scope of medical insurance. The common specificationsThe price of 100mg*24 tablets per box may be around 10,000 yuan, which is relatively expensive. The Russian version of bedaquiline sold overseas, Specification100mg*188 tablets per box, may cost around RMB 15,000 (the price may fluctuate due to the exchange rate). The pharmaceutical ingredients of bedaquiline sold domestically and abroad are basically the same, and there are currently no generic bedaquiline drugs on the market. For specific prices and drug information of overseas drugs, please consult Yaode Medical Consultant.