How effective is Upadacitinib in treating ulcerative colitis?

Upadacitinibis indicated for the treatment of adult patients with moderately to severely active ulcerative colitis who have an inadequate response to or are intolerant to one or moreTNF blockers. Combining upatinibwith other JAKinhibitors, biological therapies for ulcerative colitis, or strong immunosuppressives (such as azathioprine and cyclosporine) is not recommended. 帕替尼(Upadacitinib)治疗溃疡性结肠炎效果怎么样？

Two major studies involving988 patients show that upapatinib is effective in clearing symptoms and improving inflammation of the intestinal lining in patients with moderately to severely active ulcerative colitis whose disease has not responded to or is intolerant to other treatments.在为期八周的治疗过程中，患者每天服用一次乌帕替尼xa045 mgor placebo, the proportion of patients who took upapatinib had symptoms that were gone or nearly gone and normal or mild inflammation of the gut lining was 26% in the first study and 34% in the second study, compared with 5% and 4% of patients taking placebo. In the third study, 451 patients from the first two studies whose ulcerative colitis symptoms improved with upapatinib continued to receive 15 or 30 mg of the drug or placebo once daily. After 52 weeks of treatment, 42%of patients taking 15 mg upatinib and 30 mg Symptoms of ulcerative colitis were gone or nearly gone in 52% of patients who took upapatinib, compared with about 12% of patients who took placebo. 乌帕替尼(Upadacitinib)治疗溃疡性结肠炎效果是乐观的。 There are generic drugs in Bangladesh, the retail price is more than 15mg for 30 tablets7 more than 100. If you want to get more high-quality information, you can contact yaode, yaoWe will do our best to help you learn more about high-quality overseas drugs.