How long does it take for gilitinib to take effect?

Gilteritinib is a drug that treats a certain type of acute myeloid leukemia (AML). Based on feedback from clinical trials, gilitinib typically begins to show efficacy within a few weeks of taking it. The specific onset of action may vary depending on individual differences, but most patients will gradually observe signs such as improvement in hematological indicators, reduction in leukemia cells, and symptom relief after taking the drug. However, the therapeutic effect and onset of effect need to be evaluated based on the patient's specific situation. It is recommended that patients follow their doctor's instructions and use the drug as prescribed.

Giritinib has been approved for use in patients with newly diagnosed acute myeloid leukemia, specifically those carryingFLT3-ITD or FLT3-TKD gene mutations. The goals of treatment for newly diagnosed acute myeloid leukemia are to achieve remission, prolong progression-free survival (PFS), and improve overall survival. Giritinib is also approved for patients with relapsed/refractory acute myeloid leukemia, including those with FLT3-ITD or FLT3-TKD gene mutations.

The original drug of geritinib has been launched in China, but it has not yet been included in the medical insurance. The price of each box of 40mg*42 tablets may be more than 20,000 yuan. The price of the Hong Kong version of the original drug is about 90,000 yuan per box. The price of the European version of the original drug, 40mg*84 tablets, per box listed overseas is around RMB 210,000 (the price may fluctuate due to exchange rates), which is very expensive. Generic drugs of giritinib are currently produced and sold overseas, and their drug ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 40mg*84 tablets per box produced by a Laos pharmaceutical factory is more than 4,000 yuan (the price may fluctuate due to the exchange rate).