What are the side effects of ibrutinib?

Ibrutinib is a kinase inhibitor used to treat patients with mantle cell lymphoma (MCL) and patients who have been treated with at least one other chemotherapy drug . For the treatment of patients with chronic lymphocytic leukemia(CLL) and small lymphocytic lymphoma(SLL). It is used to treat Waldenström's macroglobulinemia(WM), to treat patients with marginal zone lymphoma(MZL), and to treat patients with chronic graft-versus-host disease(cGVHD)It can begin some time after transplantation and continue long after treatment with one or more drugs has failed.

For patients with MCL, common effects of ibrutinib include increased serum creatinine, thrombocytopenia(57%), and diarrhea(51%), bleeding(48%), neutropenia(47%), decreased hemoglobin(41%)< /span>, fatigue(41%), musculoskeletal pain(37%), peripheral edema(35%) , URIinfection(34%), nausea(31%), bruises(30%), neutropenia, grade 3 or grade 4 pan>(29%), dyspnea(27%), constipation(25%), rash(25%), abdominal pain(24%), vomiting(23%), decreased appetite(21%), cough(19%), fever(18%), stomatitis(17%), thrombocytopenia, 3 grade or 4 grade(17%), UTIviral infection< /span>(14%), pneumonia(14%), skin infection(14%), weakness(14%), muscle cramps, dyspepsia (11%), petechiae (11%), joint pain (11%), epistaxis (11%).

For cGvHD patients, common side effects of ibrutinib include fatigue(57%) and bruising(40%) span>, diarrhea(36%), thrombocytopenia(33%), stomatitis(29%), muscle cramps(29%), nausea(26%), bleeding(26%), decreased hemoglobin(24%), pneumonia(21%), upper respiratory tract infection(19%)< span>, fever(17%), headache(17%), fall(17%), Musculoskeletal pain(14%), pneumonia, grade 3 or grade 4(14%), cough(14%), peripheral edema(12%), rash(1 2%), constipation(12%), dyspnea(12%), hypokalemia(12%), 3 grade or 4 grade fatigue (12%).

For patients withCLL, common effects of ibrutinib include thrombocytopenia(71%), diarrhea(63%), and bruising(54%), neutropenia(54%), URTinfection(48%), hemoglobin decrease(44%), fatigue(31%), rash(27%), musculoskeletal pain(27%), neutropenia(27%), fever(25%), peripheral edema(23%), constipation(23%), joint pain(23%), nausea pan>(21%), stomatitis(21%), sinusitis(21%), dizziness(21%), vomiting(19%), cough(19%), muscle cramps(19%), headache(19%), skin infection(17%) , petechiae(17%), decreased appetite(17%), hypertension(17%), abdominal pain(15%) , oropharyngeal pain(15%), indigestion(13%), weakness(13%), chills(13%). There are generic drugs in Bangladesh, Laos and India. Different manufacturers have different specifications and prices. The price per box is about 1000 to 2000 more. If you want to get more high-quality information, you can contact yaode, yaoWe will do our best to help you learn more about high-quality overseas drugs.

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