Is giritinib available in China? Who can use it

As ofJanuary 2024, the original drug of Gilteritinib has been launched in China under the name Gilteritinib Fumarate Tablets. Giritinib is a drug used to treat certain hematological malignancies. It is mainly used in adult patients who have received chemotherapy and have FLT3-ITD gene mutations. Giritinib is mainly used in adult patients, and its use in children and adolescents has not been established.

Giritinib is mainly used to treat patients with FLT3-ITD gene mutations in acute myeloid leukemia (AML). FLT3-ITD mutation is a common type of AML mutation. Typically, giritinib is given to patients who have already received chemotherapy but whose disease persists or relapses. , The specific situation of each patient is different, and the final decision to use gilitinib requires a comprehensive evaluation by a doctor. Only under the guidance of a professional doctor and based on the patient's individual situation and disease characteristics can it be determined whether giritinib is suitable for use.

The original drug of giritinib has been launched in China, but it has not yet been included in the medical insurance. The price of each box of 40mg*42 tablets may be more than 20,000 yuan, and the price of the Hong Kong version of the original drug is about 90,000 yuan per box. The price of the European version of the original drug, 40mg*84 tablets, per box listed overseas is around RMB 210,000 (the price may fluctuate due to exchange rates), which is very expensive. Generic drugs of giritinib are currently produced and sold overseas, and their drug ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 40mg*84 tablets per box produced by a Laos pharmaceutical factory is more than 4,000 yuan (the price may fluctuate due to the exchange rate).