Is gilteritinib a targeted drug? What are the side effects?

Gilteritinib is a targeted anti-cancer drug. Gilteritinib is used to treat a certain type of acute myeloid leukemia(AML) that worsens or relapses after treatment with other chemotherapy drugs.

Gi Ruitinib is mainly metabolized in vitro byCYP3A4. Under steady state, the main metabolites in the human body include M17 (formed through N-dealkylation and oxidation), M16andM10 (are all formed through N-dealkylation), none of these 3 metabolites exceeds 10% of the total maternal exposure.

If you have symptoms such as hives, trouble breathing, swelling of the face, lips, tongue, or throat, contact emergency medical care immediately. Giritinibcan cause a condition called differentiation syndrome, which affects blood cells and can be fatal if left untreated. This can happen anywhere from 2 days to 3 months after you start taking giritinib. Seek medical help immediately if necessary. Symptoms of differentiation syndrome include fever, cough, difficulty breathing; bone pain; rapid weight gain or swelling of the arms, legs, armpits, groin, or neck. GIRItinib may cause serious side effects. Please contact your doctor immediately if you have any of the following conditions, including headache, confusion, mental status changes, vision loss, seizures (convulsions); Fever, chills, cough with mucus, chest pain; flu symptoms, mouth and throat ulcers; severe pain in the upper abdomen spreading to the back, nausea and vomiting, or rapid or violent heartbeat, chest beating, shortness of breath, sudden dizziness. Cancer treatment may be delayed or permanently stopped if you have certain side effects. Common side effects of giltinib may include: Nausea, vomiting, diarrhea, Constipation; Mouth or throat pain or sores; Cough, shortness of breath; Headache, dizziness; Eye problems; Muscle or joint pain; Low blood pressure; Swelling of arms or legs; fever, tiredness; decreased urination; rash, or abnormal liver function tests. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.